Pak6 | p21 (RAC1) activated kinase 6

GeneMGI:2679420

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Integument Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Pak6^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal skin coloration	1 supporting dataset	Pak6^em1(IMPC)Bay	homozygote	Early adult	1.1x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pak6.

Associated images

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Histopathology

There is no histopathology data found for Pak6.

IMPC related publications

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External links

No external links available for Pak6.

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*Pak6^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Pak6^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pak6^{tm373523(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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