Tmc8 | transmembrane channel-like gene family 8
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
17 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating alanine transaminase level | 1 supporting dataset | Tmc8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.67x10-8 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Tmc8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.32x10-6 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Tmc8tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.21x10-5 |
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External links
No external links available for Tmc8.
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| Tmc8tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Tmc8tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Tmc8tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tmc8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Tmc8tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |