Adgrl4 | adhesion G protein-coupled receptor L4

GeneMGI:2655562Synonyms: EGF-TM7 receptor, 1110033N21Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vitreous body morphology	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	5.94x10^-6
abnormal skin morphology	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	8.94x10^-6
increased neutrophil cell number	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	3.48x10^-5
increased vertical activity	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	5.78x10^-5
decreased mean corpuscular volume	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	4.92x10^-6
eye hemorrhage	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	8.12x10^-6
abnormal retina morphology	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	9.33x10^-8
abnormal liver morphology	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Adgrl4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adgrl4.

Associated images

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Histopathology

There is no histopathology data found for Adgrl4.

IMPC related publications

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External links

No external links available for Adgrl4.

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*Adgrl4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Adgrl4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Adgrl4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adgrl4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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