Yeats2 | YEATS domain containing 2

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Pigmentation Integument Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

impaired righting response1 supporting datasetYeats2em1(IMPC)JheterozygoteLate adult1.02x10-6 
embryonic lethality prior to organogenesis1 supporting datasetYeats2em1(IMPC)JhomozygoteE9.5N/A * 
hyperactivity1 supporting datasetYeats2em1(IMPC)JheterozygoteEarly adult3.75x10-5 
preweaning lethality, complete penetrance1 supporting datasetYeats2em1(IMPC)JhomozygoteEarly adultN/A * 
limb grasping1 supporting datasetYeats2em1(IMPC)JheterozygoteLate adult3.28x10-7 
abnormal coat/hair pigmentation2 supporting datasetsYeats2em1(IMPC)JheterozygoteLate adult7.72x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Yeats2em1(IMPC)JExon Deletionmouse
Yeats2tm303588(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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