Disc1 | disrupted in schizophrenia 1
GeneMGI:2447658
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Immune system Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system
12 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 5 supporting datasets | Disc1em1(IMPC)Mbp | homozygote | Early adult | 5.87x10-8 | ||
| enlarged heart | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased prepulse inhibition | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | 7.06x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| eye hemorrhage | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | 9.32x10-5 | ||
| abnormal heart morphology | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 | ||
| abnormal spleen morphology | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Disc1em1(IMPC)Mbp | homozygote | Early adult | 5.99x10-5 |
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External links
No external links available for Disc1.
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| Disc1em1(IMPC)Mbp | Exon Deletion | | mouse |