Elmod2 | ELMO/CED-12 domain containing 2

GeneMGI:2445165Synonyms: 9830169G11Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased hemoglobin content	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7x10^-5
decreased bone mineral content	2 supporting datasets	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.85x10^-10
increased circulating HDL cholesterol level	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.12x10^-7
increased circulating cholesterol level	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.24x10^-8
abnormal gait	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.91x10^-5
increased total body fat amount	2 supporting datasets	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.93x10^-8
decreased exploration in new environment	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.85x10^-5
decreased lean body mass	1 supporting dataset	Elmod2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.55x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Elmod2.

Associated images

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Histopathology

There is no histopathology data found for Elmod2.

IMPC related publications

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External links

No external links available for Elmod2.

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*Elmod2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Elmod2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Elmod2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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