Ahdc1 | AT hook, DNA binding motif, containing 1

GeneMGI:2444218Synonyms: D030015G18Rik

Physiological systems

13 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Vision/eye Skeleton

9 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lean body mass2 supporting datasetsAhdc1em1XgsheterozygoteEarly adult1.67x10-7 
abnormal retina morphology1 supporting datasetAhdc1em1XgsheterozygoteEarly adult1.55x10-7 
abnormal retina inner nuclear layer morphology1 supporting datasetAhdc1em1XgsheterozygoteEarly adult5.93x10-6 
decreased bone mineral content1 supporting datasetAhdc1em1XgsheterozygoteEarly adult7.13x10-5 
abnormal eye posterior chamber depth1 supporting datasetAhdc1em1XgsheterozygoteEarly adult6.14x10-6 
decreased bone mineral density1 supporting datasetAhdc1em1XgsheterozygoteEarly adult1.35x10-8 
increased total body fat amount1 supporting datasetAhdc1em1XgsheterozygoteEarly adult4.65x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ahdc1em1XgsPoint Mutationmouse
Ahdc1em2XgsPoint Mutationmouse
Ahdc1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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