6430548M08Rik | RIKEN cDNA 6430548M08 gene

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Renal/urinary system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes2 supporting datasets6430548M08Rikem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology2 supporting datasets6430548M08Rikem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged kidney1 supporting dataset6430548M08Rikem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting dataset6430548M08Rikem1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating alkaline phosphatase level1 supporting dataset6430548M08Rikem1(IMPC)MbphomozygoteEarly adult4.55x10-7 
increased circulating calcium level1 supporting dataset6430548M08Rikem1(IMPC)MbphomozygoteEarly adult4.6x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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6430548M08Rikem1(IMPC)MbpExon Deletionmouse
6430548M08Riktm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
6430548M08Riktm1e(KOMP)WtsiTargeted, non-conditional allelees cell
6430548M08Riktm42359(L1L2_Pgk_PM)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
6430548M08Riktm42359(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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