Wdhd1 | WD repeat and HMG-box DNA binding protein 1

GeneMGI:2443514Synonyms: AND-1, D630024B06Rik

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Endocrine/exocrine gland Growth/size/body region Liver/biliary system Cardiovascular system Mortality/aging Renal/urinary system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



enlarged thyroid gland	1 supporting dataset	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
enlarged kidney	2 supporting datasets	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
enlarged heart	1 supporting dataset	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Wdhd1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal kidney morphology	2 supporting datasets	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Wdhd1^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
increased kidney weight	2 supporting datasets	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Late adult	1.6x10^-8
increased circulating bilirubin level	1 supporting dataset	Wdhd1^{em1(IMPC)Rbrc}	heterozygote	Early adult	4.5x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Wdhd1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Wdhd1.

IMPC related publications

Loading...

External links

No external links available for Wdhd1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Wdhd1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Wdhd1^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Wdhd1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes