Gramd1c | GRAM domain containing 1C

GeneMGI:2443024Synonyms: 4921521N14Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Renal/urinary system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating aspartate transaminase level	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Late adult	1.52x10^-5
limb grasping	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.16x10^-6
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.31x10^-7
decreased startle reflex	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.48x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.89x10^-7
abnormal startle reflex	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Late adult	9.56x10^-6
decreased fasting circulating glucose level	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.26x10^-8
increased circulating triglyceride level	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Late adult	3.04x10^-5
increased urine microalbumin level	1 supporting dataset	Gramd1c^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.72x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gramd1c.

Associated images

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Histopathology

There is no histopathology data found for Gramd1c.

IMPC related publications

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External links

No external links available for Gramd1c.

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*Gramd1c^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gramd1c^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gramd1c^{tm42973(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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