Brip1 | BRCA1 interacting protein C-terminal helicase 1
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological
10 No significant impact
7 Not tested
Data collections
Gene metrics:10Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal gait | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 4.12x10-7 | ||
| increased mean corpuscular volume | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Early adult | 9.08x10-7 | ||
| thrombocytopenia | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Early adult | 7.77x10-6 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 1.91x10-10 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 4.33x10-6 | ||
| hyperactivity | 3 supporting datasets | Brip1em1(IMPC)J | homozygote | Late adult | 8.27x10-6 | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 3.15x10-5 | ||
| abnormal limb position | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 1.31x10-6 | ||
| decreased grip strength | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Late adult | 5.86x10-5 | ||
| cataract | 1 supporting dataset | Brip1em1(IMPC)J | homozygote | Early adult | 4.35x10-7 |
| | | | | | | | | | |
External links
No external links available for Brip1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Brip1em1(IMPC)J | Exon Deletion | | mouse |