Nt5dc1 | 5'-nucleotidase domain containing 1

GeneMGI:2442446Synonyms: 6030401B09Rik, Nt5c2l1

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Vision/eye Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

persistence of hyaloid vascular system1 supporting datasetNt5dc1em1(IMPC)JhomozygoteEarly adult1.06x10-6 
increased anxiety-related response1 supporting datasetNt5dc1em1(IMPC)JhomozygoteLate adult8.46x10-5 
abnormal startle reflex1 supporting datasetNt5dc1em1(IMPC)JhomozygoteLate adult2.47x10-5 
abnormal coat/hair pigmentation3 supporting datasetsNt5dc1em1(IMPC)JhomozygoteLate adult6.57x10-9 
decreased circulating glucose level1 supporting datasetNt5dc1em1(IMPC)JhomozygoteEarly adult5.22x10-5 
abnormal retina morphology1 supporting datasetNt5dc1em1(IMPC)JhomozygoteLate adult1.49x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nt5dc1em1(IMPC)JExon Deletionmouse
Nt5dc1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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