Camk1d | calcium/calmodulin-dependent protein kinase ID

GeneMGI:2442190Synonyms: CaMKIdelta, A630059D12Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

12 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

8 No significant impact

4 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased heart weight1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adult2.86x10-10 
abnormal spleen morphology2 supporting datasetsCamk1dem1(IMPC)MbphomozygoteLate adultN/A * 
decreased lean body mass1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adult2.93x10-5 
abnormal eye morphology1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen2 supporting datasetsCamk1dem1(IMPC)MbphomozygoteLate adultN/A * 
decreased bone mineral density1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adult1.29x10-5 
increased total body fat amount1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adult2.71x10-5 
increased grip strength2 supporting datasetsCamk1dem1(IMPC)MbphomozygoteLate adult1.81x10-9 
hydrometra1 supporting datasetCamk1dem1(IMPC)MbphomozygoteLate adultN/A * 
increased blood urea nitrogen level1 supporting datasetCamk1dem1(IMPC)MbphomozygoteEarly adult6.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Camk1dem1(IMPC)MbpExon Deletionmouse
Camk1dtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Camk1dtm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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