Tmem8b | transmembrane protein 8B

GeneMGI:2441680Synonyms: 4930500O05Rik

Physiological systems

21 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Nervous system Vision/eye Hematopoietic system Skeleton Renal/urinary system

11 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased prepulse inhibition	2 supporting datasets	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	4.53x10^-6
enlarged urinary bladder	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal sternum morphology	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	5.6x10^-6
enlarged stomach	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased basophil cell number	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	1.63x10^-5
abnormal ovary morphology	1 supporting dataset	Tmem8b^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem8b.

Associated images

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Histopathology

There is no histopathology data found for Tmem8b.

IMPC related publications

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External links

No external links available for Tmem8b.

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*Tmem8b^em1(IMPC)Tcp*	Inter-exon deletion	‌	mouse
*Tmem8b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tmem8b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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