Lrrtm3 | leucine rich repeat transmembrane neuronal 3

GeneMGI:2389177Synonyms: 9630044H04Rik

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Respiratory system

19 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased tidal volume3 supporting datasetsLrrtm3tm1b(KOMP)MbphomozygoteEarly adult1.27x10-7 
decreased pulmonary ventilation1 supporting datasetLrrtm3tm1b(KOMP)MbphomozygoteEarly adult1.67x10-5 
increased pulmonary ventilation2 supporting datasetsLrrtm3tm1b(KOMP)MbphomozygoteEarly adult2.08x10-5 
increased circulating aspartate transaminase level1 supporting datasetLrrtm3tm1b(KOMP)MbphomozygoteEarly adult1.67x10-5 
increased circulating serum albumin level1 supporting datasetLrrtm3tm1b(KOMP)MbphomozygoteEarly adult6.24x10-6 
decreased pulmonary respiratory rate1 supporting datasetLrrtm3tm1b(KOMP)MbphomozygoteEarly adult2.97x10-7 
increased circulating alanine transaminase level1 supporting datasetLrrtm3tm1b(KOMP)MbphomozygoteEarly adult1.27x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrrtm3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Lrrtm3tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Lrrtm3tm446896(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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