Nek9 | NIMA (never in mitosis gene a)-related expressed kinase 9

GeneMGI:2387995Synonyms: C130021H08Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Hematopoietic system Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased leukocyte cell number	1 supporting dataset	Nek9^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.21x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Nek9^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating iron level	1 supporting dataset	Nek9^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.71x10^-6
abnormal skin appearance	1 supporting dataset	Nek9^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.38x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nek9.

Associated images

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Histopathology

There is no histopathology data found for Nek9.

IMPC related publications

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External links

No external links available for Nek9.

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*Nek9^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Nek9^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nek9^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Nek9^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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