Ggnbp2 | gametogenetin binding protein 2
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Cardiovascular system Mortality/aging
13 No significant impact
5 Not tested
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues
| increased circulating alanine transaminase level | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.41x10-5 | ||
| anophthalmia | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| shortened QRS complex duration | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | heterozygote | Early adult | 2.62x10-7 | ||
| decreased circulating total protein level | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.75x10-5 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Ggnbp2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | homozygote | E15.5 | N/A * | ||
| edema | 1 supporting dataset | Ggnbp2tm1b(KOMP)Wtsi | heterozygote | E15.5 | N/A * |
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External links
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| Ggnbp2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ggnbp2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ggnbp2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |