Abca8a | ATP-binding cassette, sub-family A member 8a

GeneMGI:2386846

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vibrissa morphology	1 supporting dataset	Abca8a^em1(IMPC)J	homozygote	Early adult	1.73x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Abca8a^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased hematocrit	1 supporting dataset	Abca8a^em1(IMPC)J	homozygote	Early adult	8.16x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Abca8a.

Associated images

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Histopathology

There is no histopathology data found for Abca8a.

IMPC related publications

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External links

No external links available for Abca8a.

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*Abca8a^em1(IMPC)J*	Exon Deletion	‌	mouse
*Abca8a^{tm115090(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Abca8a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Abca8a^{tm284069(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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