Acmsd | amino carboxymuconate semialdehyde decarboxylase

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating bilirubin level1 supporting datasetAcmsdtm1b(EUCOMM)HmguhomozygoteEarly adult6.21x10-5 
increased mean platelet volume1 supporting datasetAcmsdtm1b(EUCOMM)HmguhomozygoteEarly adult1.58x10-6 
increased bone mineral density1 supporting datasetAcmsdtm1b(EUCOMM)HmguhomozygoteEarly adult6.42x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acmsdtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Acmsdtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Acmsdtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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