Tpcn2 | two pore segment channel 2
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological
18 No significant impact
2 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| increased eosinophil cell number | 1 supporting dataset | Tpcn2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.97x10-5 | ||
| abnormal vocalization | 1 supporting dataset | Tpcn2Gt(YHD437)Byg | homozygote | Early adult | 5.1x10-6 | ||
| increased circulating triglyceride level | 1 supporting dataset | Tpcn2tm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.36x10-5 | ||
| abnormal behavior | 2 supporting datasets | Tpcn2Gt(YHD437)Byg | homozygote | Early adult | 4.81x10-6 | ||
| decreased circulating sodium level | 1 supporting dataset | Tpcn2Gt(YHD437)Byg | homozygote | Early adult | 3.08x10-5 |
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External links
No external links available for Tpcn2.
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| Tpcn2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tpcn2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tpcn2tm1c(EUCOMM)Hmgu | Wild type floxed exon (post-Flp) | | mouse |
| Tpcn2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |