Kctd15 | potassium channel tetramerisation domain containing 15

GeneMGI:2385276Synonyms: MGC25497

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:41Adult tissues
0Embryo tissues

Phenotypes

increased blood urea nitrogen level1 supporting datasetKctd15tm1b(EUCOMM)WtsiheterozygoteEarly adult4.41x10-5 
abnormal embryo size1 supporting datasetKctd15tm1b(EUCOMM)WtsihomozygoteE15.5N/A * 
preweaning lethality, complete penetrance4 supporting datasetsKctd15tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased food intake1 supporting datasetKctd15tm1b(EUCOMM)WtsiheterozygoteEarly adult1.18x10-5 
increased circulating creatinine level1 supporting datasetKctd15tm1b(EUCOMM)WtsiheterozygoteEarly adult5.35x10-6 
decreased circulating alkaline phosphatase level1 supporting datasetKctd15tm1b(EUCOMM)WtsiheterozygoteEarly adult9.86x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kctd15tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Kctd15tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kctd15tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Kctd15tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Kctd15tm47323(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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