Tti2 | TELO2 interacting protein 2

GeneMGI:2384576Synonyms: BC019943

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Tti2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Tti2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.19x10^-6
increased neutrophil cell number	1 supporting dataset	Tti2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.01x10^-9
decreased lymphocyte cell number	1 supporting dataset	Tti2^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.46x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tti2.

Associated images

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Histopathology

There is no histopathology data found for Tti2.

IMPC related publications

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External links

No external links available for Tti2.

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*Tti2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tti2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tti2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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