Sdsl | serine dehydratase-like

GeneMGI:2182607Synonyms: 4432411H13Rik, SDS-RS1, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal bone structure	1 supporting dataset	Sdsl^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.5x10^-5
decreased bone mineral density	1 supporting dataset	Sdsl^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.33x10^-6
increased circulating alanine transaminase level	1 supporting dataset	Sdsl^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.91x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sdsl.

Associated images

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Histopathology

There is no histopathology data found for Sdsl.

IMPC related publications

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External links

No external links available for Sdsl.

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*Sdsl^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Sdsl^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Sdsl^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Sdsl^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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