Acbd3 | acyl-Coenzyme A binding domain containing 3

GeneMGI:2181074Synonyms: 8430407O11Rik, D1Ertd10e, +2 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetAcbd3tm1b(EUCOMM)HmguheterozygoteEarly adult4.61x10-6 
decreased circulating triglyceride level1 supporting datasetAcbd3tm1b(EUCOMM)HmguheterozygoteEarly adult1.2x10-5 
increased mean corpuscular volume1 supporting datasetAcbd3tm1b(EUCOMM)HmguheterozygoteEarly adult1.12x10-7 
preweaning lethality, complete penetrance1 supporting datasetAcbd3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetAcbd3tm1b(EUCOMM)HmguheterozygoteEarly adult5.74x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Acbd3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Acbd3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Acbd3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Acbd3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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