Il17rc | interleukin 17 receptor C
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system
11 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased body length | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | 1.55x10-6 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | 1.99x10-5 | ||
| abnormal ovary morphology | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Il17rcem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Il17rc mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Il17rc.
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| Il17rcem1(IMPC)Mbp | Inter-exon deletion | | mouse |
| Il17rctm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Il17rctm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |