Il25 | interleukin 25

GeneMGI:2155888Synonyms: Il17e, IL-17E

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Vision/eye Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal testis morphology1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adult1.39x10-5 
prolonged QRS complex duration1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adult9.14x10-5 
abnormal vitreous body morphology1 supporting datasetIl25em1(IMPC)MbphomozygoteEarly adult5.65x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il25em1(IMPC)MbpExon Deletionmouse
Il25tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Il25tm233001(L1L2_Bact_P)Reporter-tagged deletion allele (with selection cassette)targeting vector
Il25tm456563(L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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