Colec12 | collectin sub-family member 12

GeneMGI:2152907Synonyms: CL-P1, SRCL, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Nervous system Hematopoietic system Behavior/neurological Renal/urinary system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition3 supporting datasetsColec12em1(IMPC)MbphomozygoteEarly adult1.63x10-6 
increased startle reflex1 supporting datasetColec12em1(IMPC)MbphomozygoteEarly adult1.63x10-6 
hyperactivity1 supporting datasetColec12em1(IMPC)MbphomozygoteEarly adult6.34x10-5 
small kidney1 supporting datasetColec12em1(IMPC)MbphomozygoteEarly adultN/A * 
hydrocephaly1 supporting datasetColec12em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetColec12em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Colec12em1(IMPC)MbpIntra-exon deletionmouse
Colec12tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Colec12tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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