Alpk3 | alpha-kinase 3
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Growth/size/body region Muscle Cardiovascular system Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| dilated heart left ventricle | 4 supporting datasets | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 0 | ||
| enlarged heart | 2 supporting datasets | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased cardiac muscle contractility | 2 supporting datasets | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 5.9x10-8 | ||
| thick ventricular wall | 1 supporting dataset | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.89x10-15 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased heart left ventricle size | 1 supporting dataset | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.96x10-8 | ||
| increased heart weight | 1 supporting dataset | Alpk3tm1b(EUCOMM)Hmgu | homozygote | Early adult | 0 |
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External links
No external links available for Alpk3.
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| Alpk3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Alpk3tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Alpk3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |