Baz2a | bromodomain adjacent to zinc finger domain, 2A
Physiological systems
19 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Hematopoietic system Renal/urinary system
12 No significant impact
5 Not tested
Data collections
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating sodium level | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | 3.29x10-5 | ||
| small testis | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| small epididymis | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased blood urea nitrogen level | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | 1.24x10-9 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | 5.21x10-5 | ||
| small kidney | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | 3.05x10-5 | ||
| abnormal skin morphology | 1 supporting dataset | Baz2aem1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Baz2a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Baz2a.
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| Baz2aem1(IMPC)Tcp | Exon Deletion | | mouse |
| Baz2atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Baz2atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |