Nans | N-acetylneuraminic acid synthase (sialic acid synthase)
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Integument Adipose tissue Growth/size/body region Vision/eye Mortality/aging
15 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal skin morphology | 1 supporting dataset | Nansem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased total body fat amount | 2 supporting datasets | Nansem1(IMPC)Tcp | heterozygote | Early adult | 1.1x10-5 | ||
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Nansem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Nansem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased lean body mass | 2 supporting datasets | Nansem1(IMPC)Tcp | heterozygote | Early adult | 4.25x10-7 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Nansem1(IMPC)Tcp | homozygote | E12.5 | N/A * | ||
| abnormal eye morphology | 1 supporting dataset | Nansem1(IMPC)Tcp | heterozygote | Early adult | N/A * |
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External links
No external links available for Nans.
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| Nansem1(IMPC)Tcp | Exon Deletion | | mouse |
| Nanstm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Nanstm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |
| Nanstm387(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |