Otoa | otoancorin

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Hearing/vestibular/ear Nervous system Hematopoietic system Behavior/neurological

17 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response6 supporting datasetsOtoatm1.1(KOMP)VlcghomozygoteEarly adult1.26x10-11 
decreased mean corpuscular hemoglobin1 supporting datasetOtoatm1.1(KOMP)VlcghomozygoteEarly adult1.87x10-10 
decreased prepulse inhibition2 supporting datasetsOtoatm1.1(KOMP)VlcghomozygoteEarly adult1.12x10-5 
increased startle reflex1 supporting datasetOtoatm1.1(KOMP)VlcghomozygoteEarly adult8.54x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Otoatm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Otoatm1.1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)es cell
Otoatm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Otoatm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Otoatm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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