Rnf44 | ring finger protein 44

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness2 supporting datasetsRnf44em1(IMPC)BayhomozygoteEarly adult6.77x10-6 
abnormal retina inner nuclear layer morphology2 supporting datasetsRnf44em1(IMPC)BayhomozygoteEarly adult8.88x10-9 
abnormal retina outer nuclear layer morphology1 supporting datasetRnf44em1(IMPC)BayhomozygoteEarly adult5.91x10-5 
decreased exploration in new environment1 supporting datasetRnf44em1(IMPC)BayhomozygoteEarly adult2.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnf44em1(IMPC)BayExon Deletionmouse
Rnf44tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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