Peds1 | plasmanylethanolamine desaturase 1

GeneMGI:2142624Synonyms: Tmem189

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Craniofacial

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	3 supporting datasets	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.25x10^-6
decreased hematocrit	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.06x10^-7
decreased bone mineral density	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.79x10^-5
decreased hemoglobin content	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.46x10^-8
abnormal retina pigmentation	2 supporting datasets	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.35x10^-6
decreased circulating calcium level	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.62x10^-6
decreased lean body mass	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.18x10^-5
abnormal eye morphology	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	8.53x10^-5
increased mean platelet volume	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.08x10^-19
decreased circulating fructosamine level	1 supporting dataset	Peds1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.66x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Peds1.

Associated images

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Histopathology

There is no histopathology data found for Peds1.

IMPC related publications

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External links

No external links available for Peds1.

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*Peds1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Peds1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Peds1^{tm35635(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Peds1^{tm361668(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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