Mcam | melanoma cell adhesion molecule

GeneMGI:1933966Synonyms: s-endo, Muc18, +3 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Skeleton

19 No significant impact

3 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased bone mineral content1 supporting datasetMcamtm1.1(KOMP)WtsihomozygoteEarly adult8.63x10-5 
abnormal bone structure1 supporting datasetMcamtm1.1(KOMP)WtsihomozygoteEarly adult2.83x10-5 
increased vertical activity1 supporting datasetMcamtm1.1(KOMP)WtsihomozygoteEarly adult7.78x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mcamtm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
mouse
Mcamtm1.1(KOMP)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Mcamtm443744(L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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