Gar1 | GAR1 ribonucleoprotein

GeneMGI:1930948Synonyms: GAR1, C430047J18Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating chloride level1 supporting datasetGar1tm1a(EUCOMM)WtsiheterozygoteEarly adult1.25x10-5 
increased startle reflex2 supporting datasetsGar1tm1a(EUCOMM)WtsiheterozygoteEarly adult3.59x10-7 
abnormal tail movements1 supporting datasetGar1tm1a(EUCOMM)WtsiheterozygoteEarly adult3.23x10-6 
preweaning lethality, complete penetrance1 supporting datasetGar1tm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal behavior2 supporting datasetsGar1tm1a(EUCOMM)WtsiheterozygoteEarly adult2.91x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gar1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gar1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Gar1tm46895(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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