Psors1c2 | psoriasis susceptibility 1 candidate 2 (human)

GeneMGI:1930025Synonyms: SPR1, Pcg

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Mortality/aging Cardiovascular system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased heart rate	1 supporting dataset	Psors1c2^{em1(IMPC)Hmgu}	heterozygote	Early adult	9.72x10^-6
prolonged RR interval	1 supporting dataset	Psors1c2^{em1(IMPC)Hmgu}	heterozygote	Early adult	6.9x10^-9
preweaning lethality, incomplete penetrance	1 supporting dataset	Psors1c2^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Psors1c2.

Associated images

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Histopathology

There is no histopathology data found for Psors1c2.

IMPC related publications

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External links

No external links available for Psors1c2.

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*Psors1c2^{em1(IMPC)Hmgu}*	Intra-exon deletion	‌	mouse
*Psors1c2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Psors1c2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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