Zfand6 | zinc finger, AN1-type domain 6

GeneMGI:1929510Synonyms: Awp1, 3110005P07Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Renal/urinary system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:14Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased circulating HDL cholesterol level1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adult8.7x10-12 
increased mean corpuscular volume1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adult2.61x10-11 
abnormal spleen morphology1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
decreased circulating total protein level1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adult1.37x10-6 
increased circulating bilirubin level1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adult5.56x10-6 
enlarged kidney1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetZfand6em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfand6em1(IMPC)MbpInter-exon deletionmouse

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