Ruvbl1 | RuvB-like AAA ATPase 1
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
16 No significant impact
5 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular volume | 1 supporting dataset | Ruvbl1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2x10-6 | ||
| increased circulating creatinine level | 1 supporting dataset | Ruvbl1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.21x10-6 | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Ruvbl1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.6x10-13 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Ruvbl1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.06x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ruvbl1tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Ruvbl1.
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| Ruvbl1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Ruvbl1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ruvbl1tm42496(L1L2_gt0_Del_LacZ) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Ruvbl1tm42496(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |