Stk3 | serine/threonine kinase 3

GeneMGI:1928487Synonyms: MST, 0610042I06Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating aspartate transaminase level1 supporting datasetStk3em1(IMPC)HhomozygoteEarly adult2.73x10-7 
increased circulating creatinine level1 supporting datasetStk3em1(IMPC)HhomozygoteEarly adult8.76x10-5 
tremors1 supporting datasetStk3em1(IMPC)HhomozygoteEarly adult1.37x10-6 
abnormal gait1 supporting datasetStk3em1(IMPC)HhomozygoteEarly adult2.46x10-5 
increased circulating alanine transaminase level1 supporting datasetStk3em1(IMPC)HhomozygoteEarly adult2.21x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stk3em1(IMPC)HIndelmouse
Stk3em2(IMPC)HIndelmouse
Stk3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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