Mrps25 | mitochondrial ribosomal protein S25

GeneMGI:1928140Synonyms: Rpms25, 2810429N01Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Mortality/aging Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased circulating sodium level	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.38x10^-5
increased heart weight	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.15x10^-6
embryonic lethality prior to tooth bud stage	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
decreased circulating glucose level	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.63x10^-5
decreased circulating calcium level	1 supporting dataset	Mrps25^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.21x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mrps25.

Associated images

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Histopathology

There is no histopathology data found for Mrps25.

IMPC related publications

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External links

No external links available for Mrps25.

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*Mrps25^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Mrps25^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Mrps25^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Mrps25^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Mrps25^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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