Slc29a1 | solute carrier family 29 (nucleoside transporters), member 1

GeneMGI:1927073Synonyms: ENT1, 1200014D21Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

7 No significant impact

7 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

improved glucose tolerance1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult7.64x10-5 
vertebral fusion1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult3.43x10-10 
decreased heart rate1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult2.13x10-5 
increased grip strength2 supporting datasetsSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult4.82x10-5 
decreased total body fat amount1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult1.7x10-7 
abnormal rib morphology1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult9.26x10-13 
decreased prepulse inhibition1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult4.78x10-6 
decreased mean corpuscular hemoglobin concentration1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult2.01x10-7 
short tibia1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult2.38x10-5 
increased mean corpuscular volume1 supporting datasetSlc29a1tm2b(NCOM)MfgchomozygoteEarly adult1.26x10-27 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc29a1tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Slc29a1tm1a(NCOM)MfgcKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc29a1tm2a(NCOM)MfgcKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc29a1tm2b(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)mouse

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