Ascc3 | activating signal cointegrator 1 complex subunit 3
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Behavior/neurological Skeleton Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased lean body mass | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 5.63x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 7.41x10-5 | ||
| increased startle reflex | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 5.49x10-6 | ||
| long tibia | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 9.73x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ascc3em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 3.54x10-5 | ||
| increased lean body mass | 1 supporting dataset | Ascc3tm1a(EUCOMM)Hmgu | heterozygote | Early adult | 3.82x10-5 |
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External links
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| Ascc3em1(IMPC)Bay | Exon Deletion | | mouse |
| Ascc3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ascc3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |