Ankrd11 | ankyrin repeat domain 11

GeneMGI:1924337Synonyms: 3010027A04Rik, 9530048I21Rik, +2 more

Physiological systems

23 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Hearing/vestibular/ear Vision/eye Nervous system Behavior/neurological Skeleton Mortality/aging Cardiovascular system

13 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



abnormal auditory brainstem response	4 supporting datasets	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.1x10^-12
preweaning lethality, complete penetrance	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased prepulse inhibition	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.55x10^-6
abnormal retina vasculature morphology	2 supporting datasets	Ankrd11^Yod	heterozygote	Early adult	1.43x10^-5
abnormal head morphology	2 supporting datasets	Ankrd11^Yod	heterozygote	Early adult	9.55x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.46x10^-5
abnormal response to new environment	1 supporting dataset	Ankrd11^Yod	heterozygote	Early adult	6.52x10^-5
decreased body length	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.69x10^-7
decreased startle reflex	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.25x10^-7
increased circulating cholesterol level	1 supporting dataset	Ankrd11^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.62x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ankrd11.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ankrd11.

IMPC related publications

Loading...

External links

No external links available for Ankrd11.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ankrd11^{tm1(IMPC)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Ankrd11^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ankrd11^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ankrd11^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes