Jade2 | jade family PHD finger 2

GeneMGI:1924151Synonyms: 1200017K05Rik, Phf15

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Skeleton Renal/urinary system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition3 supporting datasetsJade2em1(IMPC)TcphomozygoteEarly adult3.52x10-7 
small spleen1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged urinary bladder1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased bone mineral content2 supporting datasetsJade2em1(IMPC)TcphomozygoteEarly adult2.33x10-5 
abnormal seminal vesicle morphology1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adultN/A * 
decreased fasting circulating glucose level1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adult1.1x10-6 
decreased bone mineral density1 supporting datasetJade2em1(IMPC)TcphomozygoteEarly adult3.15x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Jade2em1(IMPC)TcpExon Deletionmouse
Jade2tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Jade2tm33789(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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