Tmem67 | transmembrane protein 67

GeneMGI:1923928Synonyms: b2b1163.1Clo, b2b1291.1Clo, +1 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
11Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength1 supporting datasetTmem67em1(IMPC)JheterozygoteEarly adult6.76x10-5 
increased exploration in new environment1 supporting datasetTmem67em1(IMPC)JheterozygoteEarly adult2.74x10-5 
preweaning lethality, complete penetrance1 supporting datasetTmem67em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem67em1(IMPC)JExon Deletionmouse
Tmem67tm46735(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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