Msi2 | musashi RNA-binding protein 2

GeneMGI:1923876Synonyms: Musashi2, msi2h

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:27Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small kidney	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small spleen	2 supporting datasets	Msi2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased locomotor activity	8 supporting datasets	Msi2^em1(IMPC)Mbp	homozygote	Early adult	7.15x10^-14
persistence of hyaloid vascular system	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	5.44x10^-6
abnormal brain morphology	2 supporting datasets	Msi2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased brain size	2 supporting datasets	Msi2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased spleen weight	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	1.3x10^-26
increased mean platelet volume	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	1.72x10^-7
decreased brain weight	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	1.03x10^-28
small liver	1 supporting dataset	Msi2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Msi2.

Associated images

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Histopathology

There is no histopathology data found for Msi2.

IMPC related publications

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External links

No external links available for Msi2.

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*Msi2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Msi2^{tm353468(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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