Plekha5 | pleckstrin homology domain containing, family A member 5

GeneMGI:1923802Synonyms: PEPP2, 2810431N21Rik

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased mean corpuscular hemoglobin	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	2.47x10^-5
enlarged lymph nodes	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased spleen weight	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	9.17x10^-6
enlarged urinary bladder	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	9.96x10^-5
abnormal skin morphology	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal placement of pupils	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	4.53x10^-5
narrow eye opening	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	7.29x10^-7
cornea vascularization	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	7.8x10^-5
increased startle reflex	1 supporting dataset	Plekha5^em1(IMPC)Tcp	homozygote	Early adult	1.11x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plekha5.

Associated images

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Histopathology

There is no histopathology data found for Plekha5.

IMPC related publications

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External links

No external links available for Plekha5.

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*Plekha5^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Plekha5^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Plekha5^{tm452423(L1L2_GT2_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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