Ppp1r35 | protein phosphatase 1, regulatory subunit 35

GeneMGI:1922853Synonyms: 2010007H12Rik, 2010011D20Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Mortality/aging Cardiovascular system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal tail bud morphology	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal forebrain development	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
decreased circulating glucose level	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.21x10^-5
abnormal lens morphology	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.59x10^-5
abnormal midbrain development	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
decreased circulating chloride level	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.79x10^-5
abnormal embryo size	1 supporting dataset	Ppp1r35^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppp1r35.

Associated images

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Histopathology

There is no histopathology data found for Ppp1r35.

IMPC related publications

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External links

No external links available for Ppp1r35.

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*Ppp1r35^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ppp1r35^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ppp1r35^{tm213349(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

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