Spns1 | SPNS lysolipid transporter 1, lysophospholipid

GeneMGI:1920908Synonyms: spinster homolog, 2210013K02Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased total body fat amount	1 supporting dataset	Spns1^{tm1e(EUCOMM)Wtsi}	heterozygote	Early adult	1.74x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Spns1^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased lean body mass	2 supporting datasets	Spns1^{tm1e(EUCOMM)Wtsi}	heterozygote	Early adult	2.9x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spns1.

Associated images

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Histopathology

There is no histopathology data found for Spns1.

IMPC related publications

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External links

No external links available for Spns1.

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*Spns1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Spns1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Spns1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell mouse

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