Pgam5 | phosphoglycerate mutase family member 5

GeneMGI:1919792Synonyms: 2610528A17Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult9.72x10-8 
increased circulating creatinine level1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult4.99x10-7 
decreased circulating glucose level1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult5.64x10-8 
decreased circulating serum albumin level1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult6.47x10-8 
increased mean corpuscular volume1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult2.22x10-7 
decreased exploration in new environment2 supporting datasetsPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult8.01x10-12 
decreased erythrocyte cell number1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult2.02x10-6 
short tibia1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult9.88x10-6 
decreased circulating total protein level1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult3.62x10-6 
decreased circulating HDL cholesterol level1 supporting datasetPgam5tm1b(EUCOMM)WtsihomozygoteEarly adult7.37x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pgam5tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pgam5tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Pgam5tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pgam5tm44639(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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